Dr Meynert is the Bioinformatics Analysis Core (BAC) Manager at the MRC Institute of Genetics and Molecular Medicine (Human Genetics Unit) at the University of Edinburgh. She has been with the MRC HGU since 2010, when she joined as a Career Development Fellow in Prof Martin Taylor’s Evolutionary Genomics group. Subsequently in 2014, she moved to Prof Colin Semple’s Medical and Regulatory Genomics group as a Bioinformatician post-doctoral staff member, and was promoted to Medical Genomics Team Leader in 2016, and to BAC Manager in 2018. Dr Meynert completed a research MSc in Bioinformatics at Simon Fraser University (Vancouver, Canada) in 2005, and began her PhD studies at the European Bioinformatics Institute, University of Cambridge (Cambridge, UK) immediately afterwards, completing her degree in 2009. As BAC Manager, Dr Meynert supervises and directs a small team of post-doctoral level researchers and staff undertaking bioinformatics analyses of high throughput sequencing data for various biomedical research projects across the IGMM.
During her research career, Dr Meynert has focused primarily on exploring the applications and limitations of high throughput sequencing in the context of human genetics. She has developed methods for investigating the sensitivity of variant detection using different sequencing techniques and platforms, and is currently investigating the replicability of variant detection in formalin-fixed paraffin embedded (FFPE) tumour samples. Dr Meynert is a sought after collaborator within the IGMM and internationally, as evidenced by her strong publication record as a co-author on developmental disorder and cancer genetics projects. She has also participated in the FANTOM5 consortium producing a mammalian promoter atlas. Her current collaborations include the analysis of the largest study to date of whole genome sequencing of ovarian cancer patients, co-funded by the Scottish Genomes Partnership and AstraZeneca.
Dr Meynert was a section editor of the journal Biomolecular Detection and Quantification from 2013-2018. She has organized and hosted two Scottish NextGen Bioinformatics User Group (NextGenBUG) meetings at the IGMM in 2015 and 2017, and since 2017 has been the primary organizer of thrice-yearly Edinburgh Bioinformatics meetings. Since 2016 she has been responsible for teaching introductory high throughput sequencing analysis workshops for the Molecular Pathology MSc and Human Genetics Unit PhD students at the IGMM, and ad hoc workshops for other researchers and industrial partners.